Henry Markram ( born 28 March 1962) is an israeli Professor at the Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland and director of both the Blue Brain Project and the Human Brain Project.
Markram obtained his Bachelor of Science degree (Hons) from Cape Town University, South Africa under the supervision of Rodney Douglas and his PhD from the Weizmann Institute of Science, Israel, under the supervision of Menahem Segal. During his Ph.D. work, he discovered a link between acetylcholine and memory mechanisms by showing that acetylcholine modulates the primary receptor linked to synaptic plasticity.
Some of his work altered the relative timing of single pre- and post-synaptic action potentials to reveal a learning mechanism operating between neurons where the relative timing in the millisecond range affects the coupling strength between neurons. The importance of such timing has been reproduced in many brain regions and is known as spike timing-dependent synaptic plasticity (STDP)...
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